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About
Profesor de Pediatría y jefe interino de división
Director del programa de especialización
Cátedra de Endocrinología Pediátrica de la Fundación Greehey
Soy endocrinólogo pediátrico certificado por la junta médica en University Health y profesor de pediatría en UT Health San Antonio. Ocupo la Cátedra de Endocrinología Pediátrica de la Fundación de la Familia Greehey. Mi investigación académica se centra en la diabetes. He sido director del programa de especialización en Endocrinología Pediátrica desde 2006, cuando inicié el programa de formación de especialización. Fui elegido presidente nacional del Comité Ejecutivo de Endocrinología de la Academia de Pediatría durante los últimos seis años y también formo parte de un comité internacional de expertos en diabetes tipo 2. Obtuve mi licenciatura en la Universidad de Indiana y mi título de médico en la Facultad de Medicina de la Universidad Estatal de Wright. Realicé mi residencia en UT Southwestern, en Dallas, y mi especialización en el Hospital General de Massachusetts, en Boston.
Aspectos destacados de mi carrera:
En los últimos años, fui investigador principal de los estudios TODAY, financiados por los NIH, así como del estudio SAFARI y de los estudios Ellipse, Pioneer y Dinamo. Soy el investigador principal de los ensayos clínicos en curso del páncreas biónico, el primero de los cuales condujo a la aprobación del dispositivo en mayo de 2023.
Premios
Premio «Mejor médico de San Antonio», otorgado anualmente entre 2009 y 2021
Premio al Mejor Médico Regional de la revista SA Magazine, otorgado anualmente entre 2012-21
Mujeres excepcionales en la medicina, cada año, 2018-2021
Premio al Liderazgo de Mujeres Extraordinarias en la Medicina 2018 de la Sociedad Médica del Condado de Bexar
Dos nominaciones de la 2 UT al Premio Presidencial a la Docencia
Intereses de investigación:
Diabetes tipo 2 en la infancia: investigación de nuevas terapias e intervención ante las complicaciones
Tecnología para la diabetes tipo 1
Atención endocrinológica para niños y adolescentes
Declaración de filosofía de atención
La endocrinología es una carrera gratificante, con muchas afecciones complejas y matices que la convierten en un desafío constante. Nos gusta apoyar a nuestras familias e impartir enseñanza en todos los niveles como parte de nuestra atención clínica diaria y nuestra investigación.
Intereses y pasatiempos
En mi tiempo libre, disfruto de la lectura, los viajes y las caminatas con mi familia.
Articles & Publications
Other Publications
Castellanos LE, Russell SJ, Damiano ER, Beck RW, Shah VN, Bailey R, Calhoun P, Bird K, Mauras N; Bionic Pancreas Research Group. The Insulin-Only Bionic Pancreas Improves Glycemic Control in Non-Hispanic White and Minority Adults and Children With Type 1 Diabetes. Diabetes Care. 2023 Mar 31:dc221478. doi: 10.2337/dc22-1478. Epub ahead of print. PMID: 37000680.
Mauras N, Damiano ER, El-Khatib FH, Marak MC, Calhoun P, Ruedy KJ, Balliro C, Li Z, Beck RW, Russell SJ. Utility and Safety of Backup Insulin Regimens Generated by the Bionic Pancreas: A Randomized Study. Diabetes Technol Ther. 2023 Mar 22. doi: 10.1089/dia.2022.0461. Epub ahead of print. PMID: 36877259.
Laffel LM, Danne T, Klingensmith GJ, Tamborlane WV, Willi S, Zeitler P, Neubacher D, Marquard J; DINAMO Study Group. Efficacy and safety of the SGLT2 inhibitor empagliflozin versus placebo and the DPP-4 inhibitor linagliptin versus placebo in young people with type 2 diabetes (DINAMO): a multicentre, randomized, double-blind, parallel group, phase 3 trial. Lancet Diabetes Endocrinol. 2023 Mar;11(3):169-181. doi: 10.1016/S2213-8587(22)00387-4. Epub 2023 Feb 1. PMID: 36738751.
Susan R. Rose, Ari J. Wassner, Kupper A. Wintergerst, Nana-Hawa Yayah-Jones, Robert J. Hopkin, Janet Chuang, Jessica R. Smith, Katherine Abell, Stephen H. LaFranchi, SECTION ON ENDOCRINOLOGY EXECUTIVE COMMITTEE, COUNCIL ON GENETICS EXECUTIVE COMMITTEE. Congenital Hypothyroidism: Screening and Management. Pediatrics January 2023; 151 (1): e2022060420. 10.1542/peds.2022-060420.
El Ghormli, L., Wen, H., Uschner, D., Haymond, M. W., Hughan, K. S., Kutney, K., ... & TODAY Study Group. (2023). Trajectories of eGFR and risk of albuminuria in youth with type 2 diabetes: results from the TODAY cohort study. Pediatric Nephrology, 1-8.
Beck RW, Russell SJ, Damiano ER, El-Khatib FH, Ruedy KJ, Balliro C, Li Z, Calhoun P. A Multicenter Randomized Trial Evaluating Fast-Acting Insulin Aspart in the Bionic Pancreas in Adults with Type 1 Diabetes. Diabetes Technol Ther. 2022 Oct;24(10):681-696. doi: 10.1089/dia.2022.0167. PMID: 36173235; PMCID: PMC9529301.
Messer LH, Buckingham BA, Cogen F, Daniels M, Forlenza G, Jafri RZ, Mauras N, Muir A, Wadwa RP, White PC, Russell SJ, Damiano ER, El-Khatib FH, Ruedy KJ, Balliro CA, Li Z, Marak MC, Calhoun P, Beck RW. Positive Impact of the Bionic Pancreas on Diabetes Control in Youth 6-17 Years Old with Type 1 Diabetes: A Multicenter Randomized Trial. Diabetes Technol Ther. 2022 Oct;24(10):712-725. doi: 10.1089/dia.2022.0201.pub. PMID: 36173237; PMCID: PMC9529304.
Lynch J, Kanapka LG, Russell SJ, Damiano ER, El-Khatib FH, Ruedy KJ, Balliro C, Calhoun P, Beck RW. The Insulin-Only Bionic Pancreas Pivotal Trial Extension Study: A Multi-Center Single-Arm Evaluation of the Insulin-Only Configuration of the Bionic Pancreas in Adults and Youth with Type 1 Diabetes. Diabetes Technol Ther. 2022 Oct;24(10):726-736. doi: 10.1089/dia.2022.0341. PMID: 36173238; PMCID: PMC9529297.
Bionic Pancreas Research Group, Multicenter, Randomized Trial of a Bionic Pancreas in Type 1 Diabetes. N Engl J Med. 2022 Sep 29;387(13):1161-1172. doi: 10.1056/NEJMoa2205225. PMID: 36170500.
TODAY Study Group, & Bjornstad Petter El ghormli Laure Hughan Kara S. Laffel Lori M. Nadeau Kristen J. Rayas Maria Tesfaldet Bereket Tollefsen Sherida E. Willi Steven M. Lynch Jane. (2022). Effects of metabolic factors, race-ethnicity, and sex on the development of nephropathy in adolescents and young adults with type 2 diabetes: results from the TODAY Study. Diabetes Care, 45(5), 1056-1064.
Shah R, McKay SV, Levitt Katz LE, El Ghormli L, Anderson BJ, Casey TL, Higgins L, Izquierdo R, Wauters AD, Chang N; TODAY Study Group.(J Lynch, E Escaname, M Rayas). Adherence to multiple medications in the TODAY (Treatment Options for type 2 Diabetes in Adolescents and Youth) cohort: Effect of additional medications on adherence to primary diabetes medication. J Pediatr Endocrinol Metab. 2020 Feb 25;33(2):191-198. doi: 10.1515/jpem-2019-0315. PMID: 31809265.
MA Van Name, P Cheng, RL Gal, C Kollman, J Lynch, B Nelson, WV Tamborlane, & Pediatric Diabetes Consortium. Children and adolescents with type 1 and type 2 diabetes mellitus in the Pediatric Diabetes Consortium Registries: comparing clinical characteristics and glycaemic control. Diabetic Medicine 2020 May;37(5), 863-867. Doi:10.1111/dme.14233 Epub 2020 Feb 5. PMID: 31943374.
Kaar JL, Schmiege SJ, Drews K, Higgins J, Walders-Abramson N, Isganaitis E, Willi SM, Marcus MD, Zeitler PS, Kelsey MM. Evaluation of the longitudinal change in health behavior profiles across treatment groups in the TODAY clinical trial. (J Lynch, E Escaname, M Rayas). Pediatr Diabetes. 2020 Mar;21(2):224-232. doi: 10.1111/pedi.12976 PMID: 31886931.
Kumar, S., Lteif, A., Lynch, J., Aye, T., & Ashraf, A. (2020, June). Perspectives of Pediatric Endocrinologists on Career Choice and Strategies to Stimulate Interest in Pediatric Endocrinology Subspecialty Training. In HORMONE RESEARCH IN PAEDIATRICS (Vol. 93, No. SUPPL 1, pp. 141-142).
Arya R, Farook VS , Fowler SP, Puppala S, Chittoor G, Resendez RG, Mummidi S, Vanamala J , Almasy L, Curran JE, Comuzzie AG, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R,. Diego VP. Genetic and Environmental (Physical Fitness and Sedentary Activity) Interaction Effects on Cardiometabolic Risk Factors in Mexican American Children and Adolescents. Genetic Epidemiology 2018 Jun;42(4):378-393.
elvakumar PKC, Kabbany MN, Lopez R, Rayas MS, Lynch JL, Alkhouri N. Prevalence of Suspected Nonalcoholic Fatty Liver Disease In Lean Adolescents In The United States J Pediatr Gastroenterol Nutr 2018 Jul;67(1):75-79.
Nathan E. McWhorter, Leen Abazid, Brandon C. Gorzell, Jane L. Lynch, Umber A. Salman, Darlene F. Metter and William T. Phillips. Simultaneous blood glucose monitoring during gastric emptying scintigraphy may identify unsuspected abnormalities. Clinical Nuclear Medicine 2018 Jun;43(6):411-419.
Gidding SS, Bacha F, Bjornstad P, Levitt Katz LE, Levitsky LL, Lynch J, Tryggestad JB, Weinstock RS, El Ghormli L, Lima JAC. TODAY Study Group. Cardiac Biomarkers in Youth with Type 2 Diabetes Mellitus: Results from the TODAY Study. J Pediatr 2018 Jan;192:86-92 e5.
Arslanian S, El Ghormli L, Bacha F, Caprio S, Goland R, Haymond MW, Levitsky L, Nadeau KJ, White NH, Willi SM; TODAY Study Group.(Lynch, JL). Adiponectin, Insulin Sensitivity, β-Cell Function, and Racial/Ethnic Disparity in Treatment Failure Rates in TODAY. Diabetes Care 2017 Jan;40(1):85-93.
Farook VS, Reddivari L, Mummidi S, Puppala S, Arya R, Lopez-Alvarenga JC, Fowler SP, Chittoor G, Resendez RG, Kumar BM, Comuzzie AG, Curran JE, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R, Vanamala JK. Genetics of serum carotenoid concentrations and their correlation with obesity-related traits in Mexican American children. Am J Clin Nutr 2017 Jul;106(1):52-58.
Magge SN, Goodman E, Armstrong SC; COMMITTEE ON NUTRITION; SECTION ON ENDOCRINOLOGY; SECTION ON OBESITY. The Metabolic Syndrome in Children and Adolescents: Shifting the Focus to Cardiometabolic Risk Factor Clustering. Pediatrics 2017 Aug;140(2):e1-e14.
Hutchins J, Barajas RA, Hale DE, Escaname EN, Lynch JL. Type 2 diabetes in a 5 year old and single center experience of Type 2 diabetes in youth under 10. Pediatric Diabetes 2017 Nov;18(7):674-677.
Bachrach LK, Gordon CM; SECTION ON ENDOCRINOLOGY. Bone Densitometry in Children and Adolescents. Pediatrics 2016 Oct;138(4).
Kaplowitz P, Bloch C; Section on Endocrinology, American Academy of Pediatrics. Evaluation and Referral of Children With Signs of Early Puberty. Pediatrics 2016 Jan;137(1).
Tamboralane WV; Haymond MW; Dunger D; Shankar R; Gubitosi-Klug R; Bethin K; Karres J; Tomasi P; Libman I; Hale PH; Portman R; Klingensmith G; Reed M; Blumer J; Giacoia G; NICHD Diabetes Working Group: Lynch JL; Chilton RJ. Expanding Treatment Options for Youth With Type 2 Diabetes: Current Problems and Proposed Solutions: A White Paper From the NICHD Diabetes Working Group. Diabetes Care 2016 Mar;39(3):323-329.
Nadeau KJ, Anderson BJ, Berg EG, Chiang JL, Chou H, Copeland KC, Hannon TS, Huang TT, Lynch JL, Powell J, Sellers E, Tamborlane WV, Zeitler P. Youth-Onset Type 2 Diabetes Consensus Report: Current Status, Challenges, and Priorities. Diabetes Care 2016 Sep;39(9):1635-1642.
Farook VS, Reddivari L, Chittoor G, Puppala S, Arya R, Fowler SP, Hunt KJ, Curran JE, Comuzzie AG, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R, Vanamala J. Metabolites as novel biomarkers for childhood obesity-related traits in Mexican-American children. Pediatr Obes 2015 Aug;10(4):320-327.
Rayas MS, Willey-Courand DB, Lynch JL, Guajardo JR. Improved Screening for Cystic Fibrosis-Related Diabetes by an Integrated Care Team Using an Algorithm. Pediatric Pulmonology 2014 Oct;49(10):971-977.
Solis-Herrera C, Triplett CL, Lynch JL. Nephropathy in youth and young adults with type 2 diabetes. Current Diabetes Reports 2014 Feb;14(2).
Fowler SP, Puppala S, Arya R, Chittoor G, Farook VS, Schneider J, Resendez RG, Upadhayay RP, Vandeberg J, Hunt KJ, Bradshaw B, Cersosimo E, Vandeberg JL, Almasy L, Curran JE, Comuzzie AG, Lehman DM, Jenkinson CP, Lynch JL, Defronzo RA, Blangero J, Hale DE, Duggirala R. Genetic epidemiology of cardiometabolic risk factors and their clustering patterns in Mexican American children and adolescents: the SAFARI Study. Hum Genet 2013 Sep;132(9):1059-1071.
Orsi CM, Hale DE, Lynch JL. Pediatric obesity epidemiology. Curr Opin Endocrinol Diabetes Obes 2011 Feb;18(1):14-22. TODAY Study Group, Klingensmith GJ, Pyle L, Arslanian S, Copeland KC, Cuttler L, Kaufman F, Laffal L, Marcovina S, Tollefsen SE, Weinstock RS, Linder B.. TODAY Study Group..
Nadeau, K. J., Arslanian, S., Bacha, F., Caprio, S., Chan, C., Chao, L. C., ... & TODAY Study Group. Effect of Early Glycemic Control in Youth-Onset Type 2 Diabetes on Longer-Term Glycemic Control and β-Cell Function: Results From the TODAY Study. Diabetes Care.
Jill Weissberg-Benchell, PhD1; Anthony T. Vesco, PhD1; Jenna Shapiro, PhD1; Peter Calhoun, PhD2; Edward R. Damiano, PhD3,4; Steven J. Russell, MD, PhD4; Zoey Li, MS2; Firas H. El-Khatib, PhD4; Katrina J. Ruedy, MSPH2; Courtney A. Balliro, RN4; Roy W. Beck, MD, PhD2; and the Bionic Pancreas Research Group. Psychosocial Impact of the Insulin-Only iLet Bionic Pancreas for Adults, Youth, and Caregivers of Youth with Type 1 Diabetes, (In press).
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